THE SELFISH BRAIN THEORY
The Selfish Brain Clinical Research Group
www.selfish-brain.net 
Recent Publications:
Manfred Hallschmid, PhD
Institute of Neuroendocrinology, University of Luebeck, Germany

  1. Hallschmid M, Benedict C, Schultes B, Perras B, Fehm HL, Kern W, Born J (2007) Towards the therapeutic use of intranasal neuropeptide administration in metabolic and cognitive disorders. Regul Pept, in press

  2. Benedict C, Kern W, Schultes B, Born J, Hallschmid M (2008) Differential sensitivity of men and women to anorexigenic and memory improving effects of intranasal insulin. J Clin Endocrinol Metab, in press

  3. Hallschmid M, Benedict C, Schultes B, Born J, Kern W (2007) Obese men respond to cognitive but not to catabolic brain insulin signaling. Int J Obes (Lond), in press

  4. Schmid SM, Jauch-Chara K, Hallschmid M, Oltmanns KM, Born J, Schultes B (2007) Short-term nocturnal hypoglycaemia increases morning food intake in healthy humans. Diabet Med, in press

  5. Schmid SM, Hallschmid M, Jauch-Chara K, Bandorf N, Born J, Schultes B (2007) Sleep loss alters basal metabolic hormone secretion and modulates the dynamic counterregulatory response to hypoglycemia. J Clin Endocrinol Metab, 92(8): 3044-51

  6. Jauch-Chara K, Hallschmid M, Gais S, Schmid SM, Oltmanns KM, Colmorgen C, Born J, Schultes B (2007) Hypoglycemia during sleep impairs consolidation of declarative memory in type 1 diabetic and healthy humans. Diabetes Care, 30(8): 2040-5

  7. Jauch-Chara K, Hallschmid M, Gais S, Oltmanns KM, Peters A, Born J, Schultes B (2007) Awakening and counterregulatory response to hypoglycemia during early and late sleep. Diabetes, 56(7): 1938-42

  8. Schultes B, Jauch-Chara K, Gais S, Hallschmid M, Reiprich E, Kern W, Oltmanns KM, Peters A, Fehm HL, Born J (2007) Defective awakening response to nocturnal hypoglycemia in patients with type 1 diabetes mellitus. PLoS Med, 4(2): e69

  9. Jauch-Chara K, Hallschmid M, Schmid SM, Oltmanns KM, Peters A, Born J, Schultes B (2007) Plasma glucagon decreases during night-time sleep in type 1 diabetic patients and healthy control subjects. Diabet Med, 24(6): 684-7

  10. Pais I, Hallschmid M, Chara K, Schmid SM, Oltmanns KM, Peters A, Born J, Schultes B (2007) Mood and cognitive functions during acute euglycaemia and mild hyperglycaemia in type 2 diabetic patients. Exp Clin Endocrinol Diabetes, 115(1): 42-6

  11. Benedict C, Hallschmid M, Schultes B, Born J, Kern W (2007) Intranasal insulin to improve memory function in humans. Neuroendocrinology, 86(2): 136-42

  12. Hallschmid M, Benedict C, Born J, Kern W (2007) Targeting metabolic and cognitive pathways of the CNS by intranasal insulin administration. Expert Opin Drug Deliv, 4(4): 319-22

  13. Benedict C, Hallschmid M, Schmitz B, Schultes B, Ratter F, Fehm HL, Born J, Kern W (2007) Intranasal insulin improves memory in humans: superiority of insulin aspart. Neuropsychopharmacology, 32(1): 239-43

  14. Kern W, Benedict C, Schultes B, Plohr F, Moser A, Born J, Fehm HL, Hallschmid M (2006) Low cerebrospinal fluid insulin levels in obese humans. Diabetologia, 49(11): 2790-2

  15. Wagner U, Hallschmid M, Rasch B, Born J (2006) Brief sleep after learning keeps emotional memories alive for years. Biol Psychiatry, 60(7): 788-90

  16. Gais S, Hüllemann P, Hallschmid M, Born J (2006) Sleep-dependent surges in growth hormone do not contribute to sleep-dependent memory consolidation. Psychoneuroendocrinology, 31(6): 786-91

  17. Hallschmid M, Smolnik R, McGregor G, Born J, Fehm HL (2006) Overweight humans are resistant to the weight reducing effects of melanocortin4-10. J Clin Endocrinol Metab, 91(2): 522-5

  18. Schultes B, Peters A, Hallschmid M, Benedict C, Merl V, Oltmanns KM, Born J, Fehm HL, Kern W (2005) Modulation of food intake by glucose in patients with type 2 diabetes. Diabetes Care, 28(12): 2884-9

  19. Benedict C, Dodt C, Hallschmid M, Lepiorz M, Fehm HL, Born J, Kern W (2005) Immediate but not long-term intranasal administration of insulin raises blood pressure in human beings. Metabolism 54(10): 1356-61

  20. Gosch UW, Hueppe M, Hallschmid M, Born J, Schmucker P, Meier T (2005) Post-dural puncture headache in young adults: Comparison of two small-gauge spinal catheters with different needle design. Br J Anaesth 94(5): 657-61

  21. Benedict C, Hallschmid M, Scheibner J, Niemeyer D, Schultes B, Merl V, Fehm HL, Born J, Kern W (2005) Gut protein uptake and mechanisms of meal induced cortisol release. J Clin Endocrinol Metab 90(3): 1692-6

  22. Merl V, Peters A, Oltmanns KM, Kern W, Hubold C, Hallschmid M, Born J, Fehm 2004 Preserved circadian rhythm of serum insulin concentration at low plasma glucose during fasting in lean and overweight humans. Metabolism 53:1449-1453

  23. HL, Schultes B (2004) Preserved circadian rhythm of serum insulin concentration at low plasma glucose during fasting in lean and overweight humans. Metabolism 53(11): 1449-53

  24. Marshall L, Mölle M, Hallschmid M, Born J (2004) Transcranial direct current stimulation during sleep improves declarative memory. J Neurosci 24(44): 9985-92

  25. Hallschmid M, Benedict C, Schultes B, Fehm HL, Born J, Kern W (2004) Intranasal insulin reduces body fat in men but not in women. Diabetes 53(11): 3024-9

  26. Hallschmid M, Schultes B, Marshall L, Mölle M, Kern W, Bredthauer J, Fehm HL, Born J (2004) Transcortical direct current potential shift reflects immediate signaling of systemic insulin to the human brain. Diabetes 53(9): 2202-8

  27. Hallschmid M, Benedict C, Born J, Fehm HL, Kern W (2004) Manipulating central nervous mechanisms of food intake and body weight regulation by intranasal administration of neuropeptides in man. Physiol Behav 83(1): 55-64

  28. Benedict C, Hallschmid M, Hatke A, Schultes B, Fehm HL, Born J, Kern W (2004) Intranasal insulin improves memory in humans. Psychoneuroendocrinology 29(10): 1326-34

  29. Hallschmid M, Gais S, Meinert S, Born J (2003) NPY attenuates positive cortical DC-potential shift upon food intake in man. Psychoneuroendocrinology 28(4): 530-540

  30. Wagner U, Hallschmid M, Verleger R, Born J (2003) Signs of REM sleep dependent enhancement of implicit face memory: a repetition priming study. Biological Psychology 62(3): 197-210

  31. Fischer S, Hallschmid M, Elsner AL, Born J (2002) Sleep forms memory for finger skills. Proc Natl Acad Sci USA 99(18): 11987-91

  32. Hallschmid M, Mölle M, Fischer S, Born J (2002) EEG synchronization upon reward in man. Clin Neurophysiol 113(7): 1059-65

  33. Hallschmid M, Mölle M, Wagner U, Fehm HL, Born J (2001) Drinking related direct current (DC) positive potential shift in the human EEG depends on thirst. Neurosci Lett 311(3): 173-6

  34. Schmitt B, Mölle M, Marshall L, Hallschmid M, Born J (2001) Scalp recorded direct current (DC) potential shifts associated with food intake in hungry humans. Behav Brain Res 119(1): 85-92

  35. Schmitt B, Marshall L, Nitsche M, Hallschmid M, Eulitz C, Born J (2000) Slow cortical DC-potential responses to sweet and bitter tastes in humans. Physiol Behav 71(5): 581-7