THE SELFISH BRAIN THEORY
The Selfish Brain Clinical Research Group
www.selfish-brain.net 
Recent Publications:
Kerstin M. Oltmanns, MD
Clinic of Psychiatry and Psychotherapy, University of Luebeck, Germany

  1. Oltmanns KM, Melchert UH, Scholand-Engler HG, Howitz MC, Schultes B, Schweiger U, Hohagen F, Born J, Peters A, Pellerin L 2008 Differential energetic response of brain vs. skeletal muscle upon glycemic variations in healthy humans. Am J Physiol Regul Integr Comp Physiol 294:R12-R16

  2. Oltmanns K M, Melchert UH, Scholand-Engler HG, Schultes B, Schweiger U, Peters A 2008 Divergent effects of hyper- and hypoglycemia on circulating vascular endothelial growth factor in humans. Metabolism 57:90-94

  3. Schweiger U, Greggersen W, Rudolf S, Pusch M, Menzel T, Winn S, Hassfurth J, Fassbinder E, Kahl KG, Oltmanns KM, Hohagen F, Peters A 2008 Disturbed Glucose Disposal in Patients With Major Depression; Application of the Glucose Clamp Technique. Psychosom Med in press

  4. Jauch-Chara K, Hallschmid M, Gais S, Schmid SM, Oltmanns KM, Colmorgen C, Peters A, Born J, Schultes B 2007 Hypoglycemia during sleep impairs consolidation of declarative memory in type 1 diabetic and healthy humans. Diabetes Care 30:2040-2045

  5. Jauch-Chara K, Hallschmid M, Gais S, Oltmanns KM, Peters A, Born J, Schultes B 2007 Awakening and counterregulatory response to hypoglycemia during early and late sleep. Diabetes 56:1938-1942

  6. Ludwig AK, Weiss JM, Tauchert S, Dietze T, Rudolf S, Diedrich K, Peters A, Oltmanns KM 2007 Influence of hypo- and hyperglycemia on plasma leptin concentrations in healthy women and women with polycystic ovary syndrome (PCOS). Hum Reprod 22:1555-1561

  7. Jauch-Chara K, Hallschmid M, Schmid SM, Oltmanns KM, Peters A, Born J, Schultes B 2007 Plasma glucagon concentration during night-time sleep in type 1 diabetic patients and healthy control subjects. Diabet Med 24:684-687

  8. Schultes B, Gais S, Chara K, Reiprich E, Kern W, Oltmanns KM, Peters A, Fehm HL, Born J 2007 Defective awakening response to nocturnal hypoglycemia in patients with type 1 diabetes mellitus. PLoS Medicine 4:e69

  9. Pais I, Hallschmid M, Jauch-Chara K, Schmid S, Oltmanns KM, Peters A, Born J, Schultes B 2007 Mood and cognitive functions during acute euglycaemia and mild hy-perglycaemia in type 2 diabetic patients. Exp Clin Endocrinol Diabetes 115:42-46

  10. Peters A, Pellerin L, Dallman MF, Oltmanns KM, Born J, Schweiger U, Fehm HL 2007 Causes of Obesity: Looking Beyond the Hypothalamus. Prog Neurobiol 81:61-88

  11. Benedict C, Ghio AJ, Gehring H, Schultes B, Peters A, Oltmanns KM 2007 Transient hypoxia and downregulation of circulating prohepcidin concentrations in healthy young men. Haematologica 1:125-126

  12. Oltmanns KM, Gehring H, Rudolf S, Schultes B, Schweiger U, Born J, Fehm HL, Peters A 2006 Persistent suppression of resting energy expenditure after acute hypoxia. Metabolism 55:669-675

  13. Hubold C, Oltmanns KM, Schultes B, Jelkmann W, Born J, Fehm HL, Schweiger U, Peters A 2006 High plasma VEGF predicts low carbohydrate intake in patients with type 2 diabetes. Int J Obes (Lond) 30:1356-1361

  14. Bremer P, Baron M, Peters A, Oltmanns KM, Kern W, Fehm HL, Born J, Schultes B 2006 Hormonal, subjective, and neurocognitive responses to brief hypoglycemia in postmenopausal women and age-matched men with type 2 diabetes mellitus. Metabolism 55:331-338

  15. Oltmanns KM, Dodt B, Schultes B, Klein HH, Raspe HH, Schweiger U, Born J, Fehm HL, Peters A 2006 Cortisol correlates with disease severity in a population study of type 2 diabetic patients. Eur J Endocrinol 154:325-331

  16. Oltmanns KM, Gehring H, Rudolf S, Schultes B, Hackenberg C, Schweiger U, Born J, Peters A 2006 Acute hypoxia decreases plasma VEGF concentration in healthy young men. Am J Physiol Endocrinol Metab 290:E434-439

  17. Schultes B, Peters A, Hallschmid M, Benedict C, Merl V, Oltmanns KM, Born J, Fehm HL, Kern W 2005 Modulation of Food Intake by Glucose in Patients With Type 2 Diabetes. Diabetes Care 28:2884-2889

  18. Bahlmann L, Oltmanns KM, Peters A, Poeling J, Schwemmer U, Heringlake M, Klaus S 2005 Metabolic stress during hypoglycaemia clamp assessed by microdialysis. Minerva Anestesiol 71:711-716

  19. Merl V, Peters A, Oltmanns KM, Kern W, Hubold C, Fehm HL, Born J, Schultes B 2005 Antecedent hypoglycemia attenuates Vascular Endothelial Growth Factor response to subsequent hypoglycaemia. Diabet Med 22:1278-1281

  20. Merl V, Peters A, Oltmanns KM, Kern W, Born J, Fehm HL, Schultes B 2005 Serum adiponectin concentrations during a 72-hour fast in over- and normal-weight humans. Int J Obes Relat Metab Disord 29:998-1001

  21. Oltmanns KM, Fehm HL, Peters A 2005 Chronic fentanyl application induces adreno-cortical insufficiency. J Intern Med 257:478-480

  22. Schultes B, Peters A, Kern W, Gais S, Oltmanns KM, Fehm HL, Born J 2005 Process-ing of food stimuli is selectively enhanced during insulin-induced hypoglycemia in healthy men. Psychoneuroendocrinology 30:496-504

  23. Oltmanns KM, Peters A, Kern W, Fehm HL, Born J, Schultes B 2005 Preserved inhibi-tory effect of recurrent hypoglycaemia on the male gonadotrophic axis. Clin Endocrinol (Oxf) 62:217-222

  24. Schultes B, Kern W, Oltmanns KM, Peters A, Gais S, Fehm HL, Born J 2005 Differential adaptation of neurocognitive brain functions to recurrent hypoglycemia in healthy men. Psychoneuroendocrinology 30:149-161

  25. Merl V, Peters A, Oltmanns KM, Kern W, Hubold C, Hallschmid M, Born J, Fehm HL, Schultes B 2004 Preserved Circadian Rhythm of Serum Insulin Concentration at Low Plasma Glucose During Fasting in Lean and Overweight Humans. Metabolism 53:1449-1453

  26. Merl V, Kern W, Peters A, Oltmanns KM, Gais S, Born J, Fehm HL, Schultes B 2004 Differences between nighttime and daytime hypoglycemia counterregulation in healthy humans. Metabolism 53:894-898

  27. Peters A, Schweiger U, Pellerin L, Hubold C, Oltmanns KM, Conrad M, Schultes B, Born J, Fehm HL 2004 The selfish brain: competition for energy resources. Neurosci Biobehav Rev 28:143-180

  28. Oltmanns KM, Gehring H, Rudolf S, Schultes B, Rook S, Schweiger U, Born J, Fehm HL, Peters A 2004 Hypoxia Causes Glucose Intolerance in Humans. Am J Respir Crit Care Med 169:1231-1237

  29. Oltmanns KM, Deininger E, Wellhoener P, Schultes B, Kern W, Marx E, Dominiak P, Born J, Fehm HL, Peters A 2003 Influence of captopril on symptomatic and hormonal re-sponses to hypoglycaemia in humans. Br J Clin Pharmacol 55:347-353

  30. Schultes B, Oltmanns KM, Kern W, Fehm HL, Born J, Peters A 2003 Modulation of hunger by plasma glucose and metformin. J Clin Endocrinol Metab 88:1133-1141

  31. Schultes B, Oltmanns KM, Kern W, Born J., Fehm HL, Peters A 2002 Acute and pro-longed effects of insulin-induced hypoglycemia on the pituitary-thyroid axis in humans. Metabolism 51:1370-1374

  32. Fruehwald-Schultes B, Oltmanns KM, Kern W, Born J., Fehm HL, Peters A 2002 The effect of experimentally induced insulin resistance on the leptin response to hyperinsu-linaemia. Int J Obes Relat Metab Disord 26:510-516

  33. Fruehwald-Schultes B, Oltmanns KM, Toschek B, Sopke S, Kern W, Born J, Fehm HL, Peters A 2002 Short-term treatment with metformin decreases serum leptin concentra-tion without affecting body weight and body fat content in normal-weight healthy men. Me-tabolism 51:531-536

  34. Deininger E, Oltmanns KM, Wellhoener P, Fruehwald-Schultes B, Kern W, Heuer B, Dominiak P, Born J, Fehm HL, Peters A 2001 Losartan attenuates symptomatic and hormonal responses to hypoglycemia in humans. Clin Pharmacol Ther 70:362-369

  35. Oltmanns KM, Fruehwald-Schultes B, Kern W, Born J, Fehm HL, Peters A 2001 Hypoglycemia, but not insulin, acutely decreases LH and T secretion in men. J Clin Endocrinol Metab 86:4913-4919

  36. Fruehwald-Schultes B, Kern W, Oltmanns KM, Sopke S, Toschek B, Born J, Fehm HL, Peters A 2001 Metformin does not adversely affect hormonal and symptomatic responses to recurrent hypoglycemia. J Clin Endocrinol Metab 86:4187-4192

  37. Weiss JM, Oltmanns KM, Gurke EM, Polack S, Eick F, Felberbaum R, Diedrich K, Ortmann O 2001 Actions of gonadotropin-releasing hormone antagonists on steroidogenesis in human granulosa lutein cells. Eur J Endocrinol 144:677-685